Author

E. M. Schoof

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 2 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Assay:proteomics· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:protein structure prediction· 2 Approach:statistical model· 2

Frequent Co-Authors

J. E. Dick· 2 shared L. Salmena· 2 shared M. D. Minden· 2 shared A. A. Shishkin· 1 shared A. G. Trotman-Grant· 1 shared A. G. Zeng· 1 shared A. He· 1 shared A. J. Murison· 1 shared

Activity by Year

2021-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersCell Biology

J. E. Dick

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Refining Spatial Proteomics by Mass Spectrometry: An Efficient Workflow Tailored for Archival Tissue

R. Daucke, C. V. Rift, N. S. Bager, K. Saxena, P. R. Koffeldt, J. Woessmann, V. Petrosius, E. S. Rugiu, B. W. Kristensen, P. Klausen, E. M. Schoof

This paper develops an efficient workflow for spatial proteomics on FFPE tissue using low-input material, showing that EpCAM staining improves protein identification compared to H&E staining.

BMC Methods · Apr 22, 2026Peer-reviewedBioengineering

Lipid levels correlate with neuronal and dopaminergic markers during the differentiation of SH-SY5Y cells

F. R. Marlet, S. S. Munoz, N. Sotiraki, J. N. Eliasen, J. P. Woessmann, J. E. Dreier, E. M. Schoof, K. A. Kohlmeier, K. Maeda, C. Galvagnion

This study characterizes lipidome changes during SH-SY5Y cell differentiation into dopaminergic neurons and links lipid levels to neuronal and dopaminergic markers.

bioRxiv · Sep 1, 2023Cell Biology

Optimizing linear ion trap data independent acquisition towards single cell proteomics

T. Phlairaharn, Z. Ye, E. Krismer, A.-K. Pedersen, M. Pietzner, J. V. Olsen, E. M. Schoof, B. C. Searle

This study optimizes linear ion trap data independent acquisition for single-cell proteomics, showing quantitative accuracy down to 0.5 ng on column using LIT-based libraries from as few as 40 cells.

bioRxiv · Feb 21, 2023Biochemistry

High-throughput and high-sensitivity biomarker monitoring in body fluid by FAIMS-enhanced fast LC SureQuant™ IS targeted quantitation

K. Kalogeropoulos, S. Savickas, A. M. Haack, C. A. Larsen, J. Mikosinski, E. M. Schoof, H. Smola, L. Bundgaard, U. auf dem Keller

The paper withdraws its manuscript due to the need for further analysis of conclusions.

bioRxiv · Mar 22, 2022Biochemistry

Real-Time Search Assisted Acquisition on a Tribrid Mass Spectrometer Improves Coverage in Multiplexed Single-Cell Proteomics

B. Furtwängler, N. Üresin, K. Motamedchaboki, R. Huguet, D. Lopez-Ferrer, V. Zabrouskov, B. T. Porse, E. M. Schoof

The paper introduces RETICLE, a new acquisition strategy for multiplexed single-cell proteomics that improves proteome coverage and quantitative accuracy using real-time search and SPS-MS3 on a Tribrid mass spectrometer.

bioRxiv · Aug 16, 2021Biochemistry

Identification of the Global miR-130a Targetome Reveals a Novel Role for TBL1XR1 in Hematopoietic Stem Cell Self-Renewal and t(8;21) AML

G. Krivdova, V. Voisin, E. M. Schoof, S. A. Marhon, A. J. Murison, J. L. McLeod, M. Gabra, A. G. Zeng, E. L. Van Nostrand, S. J. Aigner, A. A. Shishkin, B. A. Yee, K. G. Hermans, A. G. Trotman-Grant, N. Mbong, , E. R. Lechman

This study identifies miR-130a as a regulator of HSC self-renewal and differentiation, with TBL1XR1 as a key target, and shows its role in maintaining the oncogenic program in t(8;21) AML.

bioRxiv · Jul 30, 2021Cell Biology

INPP4B drives lysosome biogenesis to restrict leukemic stem cell differentiation and promote leukemogenesis

J. F. Woolley, K. Chen, G. T. Saffi, G. E. Genc, D. K. C. Lee, I. Dzneladze, R. He, J. T.-S. Chow, M. M. Gabra, M. H. Son, C. M. P. Melo, C. A. Newell, A. He, E. M. Schoof, S. Z. Xie, , L. Salmena

This study identifies INPP4B's role in promoting leukemic stem cell (LSC) survival by enhancing lysosome biogenesis, leading to poor AML prognosis and suggesting therapeutic targets.

bioRxiv · Mar 25, 2021 · PreprintCancer Biology