CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels
A. B. Gonçalves, S. K. Hasselbalch, B. B. Joensen, S. Patzke, P. Martens, S. K. Ohlsen, M. Quinodoz, K. Nikopoulus, R. Suleiman, M. P. D. Jeppesen, C. Weiss, S. T. Christensen, C. Rivolta, J. S. Andersen, P. Farinelli, L. B. Pedersen
This study identifies CEP78's role in ciliogenesis by showing it interacts with CEP350 and the EDD1 ubiquitin ligase complex to regulate CP110 levels.
bioRxiv · Oct 5, 2020Cell Biology