P. Muralidhar

Polygenic outcomes of sexually antagonistic selection

This study examines how polygenic phenotypes evolve under sexually antagonistic selection, showing rapid divergence toward sex-specific optima and the role of sex chromosomes in shaping phenotypic variance.

Recombination and selection against introgressed DNA

This paper uses mathematical modeling and simulations to show that recombination rate influences the purging of introgressed DNA, with implications for genomic signals of historical introgression.

Mate choice enhances post-zygotic barriers to gene flow via ancestry bundling

The paper shows mate choice enhances post-zygotic barriers to gene flow by bundling ancestry in offspring, increasing purging of introgressed DNA through increased ancestry variance.

Dominance shifts increase the likelihood of soft selective sweeps

The paper shows dominance shifts increase the likelihood of soft selective sweeps during adaptation to new environments, using Drosophila pesticide resistance as a case study.

On the logic of Fisherian sexual selection

This paper analyzes Fisherian sexual selection in diploids, showing it operates through two channels—trans and cis—distinguishing diploid from haploid models.

Drift-Induced Selection Between Male And Female Heterogamety

The paper shows that drift-induced selection, not neutrality, drives evolutionary transitions between male and female heterogamety by favoring dominant sex-determining chromosomes.