Minus one frameshifted puromycin N-acetyltransferase is targeted to the nucleolus: sporadic but reproducible chimera formation by a transfected Lc3b construct
A. A. Thekkinghat, P. N. Rangarajan
The paper reports that a transfected Lc3b construct forms a nucleolar chimera with a puromycin resistance gene through a -1 frameshift, leading to a protein with altered properties.
bioRxiv · Feb 17, 2022 · PreprintCell Biology