KLIPP - a precision CRISPR approach to target structural variant junctions in cancer
H. Yang, R. S. Hulbatte, A. Kellher, N. Gratsch, Y. Wang, P. Palmbos, M. Ljungman
KLIPP uses CRISPR/Cas9 to target cancer-specific structural variant junctions, inducing DNA breaks and cell death in tumor cells with high specificity.
bioRxiv · May 10, 2023 · PreprintCancer Biology