Author

P. Pauwels

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Bogaerts· 1 shared A. Lin· 1 shared C. Blanquart· 1 shared C. Deben· 1 shared C. Meiller· 1 shared D. Jean· 1 shared E. C. De La Hoz· 1 shared E. Raspe· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. Bogaerts

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2 papers

Recent·Most cited

Preclinical evaluation of CDK4 phosphorylation predicts high sensitivity of malignant pleural mesotheliomas to CDK4/6 inhibition

S. Paternot, E. Raspe, C. Meiller, M. Tarabichi, J.-B. Assie, F. Libert, M. Remmelink, X. Bisteau, P. Pauwels, Y. Blum, N. Le Stang, S. Tabone-Eglinger, F. Galateau-Salle, C. Blanquart, J. P. Van Meerbeeck, , P. P. Roger

This study shows that CDK4 phosphorylation predicts sensitivity of malignant pleural mesothelioma to CDK4/6 inhibitors, with 80% of tumors expressing phosphorylated CDK4.

bioRxiv · Apr 11, 2022Cancer Biology

OrBITS: A High-throughput, time-lapse, and label-free drug screening platform for patient-derived 3D organoids

C. Deben, E. C. De La Hoz, M. Le Compte, P. Van Schil, J. M. Hendriks, P. Lauwers, S. K. Yogeswaran, F. Lardon, S. Van Laere, P. Pauwels, A. Bogaerts, E. Smits, S. Vanlanduit, A. Lin

The paper introduces OrBITS, a software for automated live-cell imaging of organoids, validated against standard assays, and demonstrates its utility in drug screening and patient stratification.

bioRxiv · Sep 9, 2021 · PreprintCancer Biology