Author

P. Pfenninger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

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Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1

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J. Abe· 1 shared L. Yerly· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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1 shared paperImmunology

J. Abe

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1 paper

Recent·Most cited

Naive and in vitro-activated primary mouse CD8+ T cells retain in vivo immune responsiveness after electroporation-based CRISPR/Cas9 genetic engineering

P. Pfenninger, L. Yerly, J. Abe

This study shows that nucleofection-based CRISPR/Cas9 editing preserves in vivo immune function of naive CD8+ T cells but slightly impairs in vitro-activated cells, with varying gene product decay rates.

bioRxiv · Sep 14, 2021Immunology