Pharmacology & ToxicologybioRxiv
Simultaneous in vitro simulation of multiple antimicrobial agents with different elimination half-lives in a pre-clinical infection model
I. Kesisoglou, B. Eales, K. R. Ledesma…·M. Nikolaou
The paper develops a method to simulate the pharmacokinetics of multiple antimicrobial agents in vitro, validated with three antibiotics having different elimination half-lives.
DOI 10.1016/j.compchemeng.2021.107540