Quantitative mass spectrometry to interrogate proteomic heterogeneity in metastatic lung adenocarcinoma and validate a novel somatic mutation CDK12-G879V
X. Zhang, K. D. Nguyen, P. Rudnick, N. Roper, E. Kawaler, T. K. Maity, S. Awasthi, S. Gao, R. Biswas, A. Venugopalan, C. M. Cultraro, D. Fenyo, U. Guha
The paper uses quantitative mass spectrometry to analyze proteomic and phosphoproteomic changes in metastatic lung adenocarcinoma and validates a novel somatic mutation CDK12-G879V associated with chemotherapy sensitivity.
bioRxiv · Aug 22, 2018Cancer Biology