Human-like NSG mouse glycoproteins sialylation pattern changes the phenotype of human lymphocytes and sensitivity to HIV-1 infection
R. S. Dagur, A. Branch Woods, S. Mathews, P. S. Joshi, R. M. Quadros, D. W. Harms, Y. Cheng, S. M. Miles, S. J. Pirruccello, C. B. Gurumurthy, S. Gorantla, L. Y. Poluektova
This paper creates a new mouse model with human-like sialylation patterns that improves human immune cell transplantation and HIV-1 infection sensitivity.
bioRxiv · Aug 31, 2018Immunology