A Human Tumor Virus Recruits HSP70 Chaperone to Remodel Its Replisome on DNA
L. Wan, X. Li, P. Vittot, J. Brodsky, P. Wipf, P. S. Moore, Yuan Chang
This study shows that MCV small T protein recruits HSP70 to facilitate LT helicase remodeling and DNA unwinding, revealing a conserved mechanism for replication complex assembly.
bioRxiv · Nov 9, 2026 · PreprintMolecular Biology