Author

P. Sharpe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 3 Assay:scRNA-seq· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1

Frequent Co-Authors

V. Booth· 2 shared A. A. Volponi· 1 shared A. Caetano· 1 shared A. J. Caetano· 1 shared A. Volponi· 1 shared E. DAgostino· 1 shared E. M. D'Agostino· 1 shared F. Karim· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

V. Booth

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mapping the Spatial Dynamics of the Human Oral Mucosa in Chronic Inflammatory Disease

A. J. Caetano, Y. Redhead, F. Karim, P. Dhami, S. Kannambath, R. Nuamah, A. A. Volponi, L. Nibali, V. Booth, E. M. D'Agostino, P. Sharpe

The paper maps spatial dynamics in human oral mucosa using single-cell and spatial transcriptomics to identify immune programs and pathogenic fibroblasts in chronic inflammation.

bioRxiv · Jul 5, 2022Cell Biology

Telocytes regulate macrophages in periodontal disease

P. Sharpe, J. Zhao

The paper identifies telocytes as regulators of macrophage activity in periodontitis through HGF/c-Met signaling, showing they shift macrophages to an M1/M2 hybrid state.

bioRxiv · Jun 3, 2021Cell Biology

Defining human mesenchymal and epithelial heterogeneity in response to oral inflammatory disease

P. Sharpe, A. Caetano, V. Yianni, A. Volponi, V. Booth, E. DAgostino

This study uses single-cell transcriptomics to characterize epithelial and mesenchymal heterogeneity in human oral mucosa during inflammatory disease, identifying cell-type changes and potential intercellular hubs involved in inflammation.

bioRxiv · Sep 2, 2020Cell Biology