Comparison of the full distribution of fitness effects of new amino acid mutations across great apes
D. Castellano, M. Coll Macia, P. Tataru, T. Bataillon, K. Munch
The paper compares the distribution of fitness effects of new amino acid mutations across great apes and finds similar deleterious DFE shapes but varying negative selection strength related to population size and epistasis.
bioRxiv · Jul 10, 2019Evolutionary Biology