K. Munch

Genome-wide coancestry reveals details of ancient and recent male-driven reticulation in baboons

Genomic data from 225 baboons reveal novel inter-species gene flow sites and local admixture effects across different lineages.

Extraordinary selection on the human X chromosome associated with archaic admixture

The paper identifies X chromosome regions with strong selection in non-African populations, showing no Neanderthal ancestry, and links them to ancient selection events.

Impact of mutation rate and selection at linked sites on DNA variation across the genomes of humans and other homininae

The paper examines how mutation rate, recombination rate, and selection at linked sites influence DNA diversity across homininae genomes, showing their interactions with genetic drift.

Comparison of the full distribution of fitness effects of new amino acid mutations across great apes

The paper compares the distribution of fitness effects of new amino acid mutations across great apes and finds similar deleterious DFE shapes but varying negative selection strength related to population size and epistasis.

Viruses rule over adaptation in conserved human proteins

The paper shows that virus-interacting proteins, even when conserved across species, experience high adaptive evolution, with viruses driving over 75% of adaptation in the most conserved human proteins.

Positively selected effector genes and their contribution to virulence in the smut fungus Sporisorium reilianum

This study identifies positively selected genes in the smut fungus Sporisorium reilianum and assesses their role in virulence, finding that only one gene deletion significantly reduces virulence.

Dynamic copy number evolution of X- and Y-linked ampliconic genes in human populations

The paper investigates copy number variation and coding variation of X- and Y-linked ampliconic genes in human populations using the Simons Genome Diversity Project, revealing extensive standing variation and rapid turnover.