Author

P. Umana

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:imaging· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

A. Beilhack· 1 shared A. M. Giusti· 1 shared A. Varol· 1 shared A.-K. Wolf· 1 shared C. Klein· 1 shared D. Speziale· 1 shared E. Menietti· 1 shared F. Cremasco· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Beilhack

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

ROCKETS - a novel one-for-all toolbox for light sheet microscopy in drug discovery

J. P. Mueller, M. Dobosz, N. O'Brien, A. M. Giusti, M. Lechmann, F. Osl, A.-K. Wolf, M. Sauer, F. Herting, P. Umana, T. Poeschinger, A. Beilhack

ROCKETS provides a standardized protocol for processing and imaging mouse tissues with LSFM, enabling comprehensive biodistribution analysis of immunotherapies.

Frontiers in Immunology · Feb 7, 2023Peer-reviewedPharmacology & Toxicology

Cross-Linking of T cell to B cell lymphoma by the T cell bispecific antibody CD20-TCB induces IFNγ/CXCL10-dependent peripheral T cell recruitment in humanized murine model.

F. Cremasco, E. Menietti, D. Speziale, J. Sam, S. Sammicheli, M. Richard, A. Varol, C. Klein, P. Umana, M. Bacac, S. Colombetti, M. Perro

This study investigates how CD20-TCB induces T cell-tumor synapses and recruitment in a humanized murine model of DLBCL, revealing a triple mechanism involving synapse formation, resident T cell proliferation, and peripheral T cell recruitment.

bioRxiv · Oct 9, 2020Immunology