Ligation of random oligomers leads to emergence of autocatalytic sequence network
P. W. Kudella, A. V. Tkachenko, S. Maslov, D. Braun
This study shows how nontrivial sequence patterns emerge from random DNA strands through templated ligation and temperature cycling, resembling Darwinian evolution.
bioRxiv · Aug 18, 2020 · PreprintBiophysics