Author

P.-S. Ng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Organism:human· 4 Assay:bulk RNA-seq· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Assay:whole-exome sequencing· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

C.-H. Yip· 4 shared J.-W. Pan· 4 shared P. Rajadurai· 4 shared S.-H. Teo· 4 shared C. Caldas· 3 shared O. M. Rueda· 3 shared S. N. Hasan· 3 shared S.-F. Chin· 3 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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4 shared papersCancer Biology

C.-H. Yip

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4 papers

Recent·Most cited

Gene expression signature for predicting homologous recombination deficiency in triple-negative breast cancer

J.-W. Pan, Z.-C. Tan, P.-S. Ng, M. M. A. Zabidi, P. Nur Fatin, J.-Y. Teo, S. N. Hasan, T. Islam, L.-Y. Teoh, S. Jamaris, M.-H. See, C.-H. Yip, P. Rajadurai, L.-M. Looi, A. M. Taib, , S.-H. Teo

The paper develops a gene expression classifier to predict homologous recombination deficiency in triple-negative breast cancer using RNA-seq and WES data from a Malaysian cohort, achieving high accuracy in validation datasets.

bioRxiv · Jun 8, 2022Cancer Biology

TP53 somatic mutations in Asian breast cancer are associated with subtype-specific effects

M. E. Ragu, J. M. C. Lim, P.-S. Ng, C.-H. Yip, P. Rajadurai, S.-H. Teo, J.-W. Pan

The paper analyzes TP53 mutations in Asian breast cancer samples and finds subtype-specific effects on HR deficiency and transcriptional changes.

bioRxiv · Mar 31, 2022 · PreprintCancer Biology

Germline APOBEC3B deletion in Asian women increases somatic hypermutation in breast cancer that is associated with Her2 subtype, PIK3CA mutations, immune activation, and increased survival

J.-W. Pan, M. M. A. Zabidi, B.-K. Chong, M.-Y. Meng, P.-S. Ng, S. N. Hasan, B. Sandey, S. Bahnu, P. Rajadurai, C.-H. Yip, O. M. Rueda, C. Caldas, S.-F. Chin, S.-H. Teo

bioRxiv · Jun 4, 2020Cancer Biology

The Molecular Landscape of Asian Breast Cancers Reveals Clinically Relevant Population-Specific Differences

J.-W. Pan, M. M. Ahmad Zabidi, P.-S. Ng, M.-Y. Meng, S. N. Hasan, B. Sandey, S. J. Sammut, C.-H. Yip, P. Rajadurai, O. M. Rueda, C. Caldas, S.-F. Chin, S.-H. Teo

This study analyzes molecular profiles of 560 Asian breast tumors, revealing population-specific differences in subtypes, mutations, and immune scores compared to Caucasian populations.

bioRxiv · Apr 9, 2020Cancer Biology