Design to Data for mutants of β-glucosidase B from Paenibacillus polymyxa: Y333F, A88E, L219Q, A408H, Y173L, E340S, and Y422F
Alexandra Maduros, Leila Farinsky, Pagkratios Tagkopoulos, Ashley Vater, Justin B. Siegel
This study evaluates seven single-point mutants of β-glucosidase B using computational design and experimental analysis, finding weak correlations between predicted thermodynamic stability and enzyme properties.
bioRxiv · Feb 5, 2026 · PreprintBiochemistry