Author

Ashley Vater

University of California, DavisORCID 0000-0001-6003-5086Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 3 Approach:experimental assay· 3 Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Organism:bacteria (other)· 1 Assay:proteomics· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Justin B. SiegeliD· 3 shared Alexandra Maduros· 1 shared Claire Huntington· 1 shared Leila Farinsky· 1 shared Nicholas Li· 1 shared Pagkratios Tagkopoulos· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 8 mutual co-author links

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3 shared papersBiochemistry

Justin B. SiegelORCID

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintFeb 5, 2026

Design to Data for mutants of β-glucosidase B from Paenibacillus polymyxa: Y333F, A88E, L219Q, A408H, Y173L, E340S, and Y422F

Alexandra Maduros, Leila Farinsky, Pagkratios Tagkopoulos…·Justin B. Siegel

This study evaluates seven single-point mutants of β-glucosidase B using computational design and experimental analysis, finding weak correlations between predicted thermodynamic stability and enzyme properties.

DOI 10.64898/2026.02.04.703908

protein structureexperimental assay

𝕏 PostBluesky

BioengineeringbioRxivPreprintNov 24, 2025

Design to Data for mutants of β-glucosidase B from Paenibacillus polymyxa: N160L, N160S, N160C, N160M, N160G

Nicholas Li, Ashley Vater, Justin B. Siegel

The paper expands a Design to Data dataset with kinetic and thermal analysis of BglB variants, showing a weak link between Foldit energy and thermal stability.

1 citation

protein structureexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivPreprintMay 22, 2025

Design to Data for mutants of β-glucosidase B from Paenibacillus polymyxa: L336M, L336A, L336S, L336H, D35E, D35W

Claire Huntington, Ashley Vater, Justin B. Siegel

The paper reports experimental data on six single-point mutants of β-glucosidase B from Paenibacillus polymyxa, analyzing their kinetic and thermal stability to improve computational enzyme modeling.

DOI 10.1101/2025.05.22.655130

bacteria (other)proteomics

𝕏 PostBluesky