Author

Pamela J Shaw

Royal Hallamshire Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Alessandro Pristerà· 1 shared Anastasia Thoma· 1 shared Ella Simmonite· 1 shared Emily Mossman· 1 shared Fatima-ezzahra Errachidi· 1 shared Gauri BhosaleiD· 1 shared Heather MortiboysiD· 1 shared Laura FerraiuoloiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Alessandro Pristerà

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1 paper

Recent·Most cited

Identification and small molecule rescue of mitochondrial dysfunction phenotype which converges across Leigh Syndrome and Huntington's Disease patient fibroblasts.

Naomi Hartopp, Laura V. Ellis, Rachel M. Hughes, Emily Mossman, Ella Simmonite, Anastasia Thoma, Fatima-ezzahra Errachidi, Gauri Bhosale, Alessandro Pristerà, Scott P. Allen, Laura Ferraiuolo, Pamela J Shaw, Oliver Bandmann, Heather Mortiboys

This study identifies a common mitochondrial dysfunction phenotype in Leigh syndrome and Huntington's disease patient fibroblasts and finds that the AMPK activator A769662 rescues this phenotype in both conditions.

bioRxiv · Jun 8, 2026 · PreprintNeuroscience