Sensitivity to temozolomide of cell lines derived from brain tumours and melanomas: relationship to MGMT gene expression
Bruce C. Baguley, Wayne R. Joseph, Pamela M. Murray, Kathryn M. Stowell, Euphemia Yee Leung, Elaine S Marshall
The paper assesses temozolomide sensitivity in melanoma and glioblastoma cell lines and finds a strong correlation with MGMT mRNA expression but only partial correlation with MGMT promoter methylation.
bioRxiv · Nov 30, 2024 · PreprintCancer Biology