Amyloid-β targeting immunisation in aged non-human primate (Microcebus murinus)
Stéphanie G. Trouche, Allal Boutajangout, Ayodeji A. Asuni, Pascaline Fontès, Einar M. Sigurdsson, Jean‐Michel Verdier, Nadine Mestre‐Francés
This study evaluates the safety and efficacy of an Aβ derivative vaccine in aged non-human primates, finding reduced intracellular Aβ and trends of cognitive improvement without adverse effects.
bioRxiv · Aug 5, 2022Neuroscience