NeurosciencebioRxiv
Amyloid-β targeting immunisation in aged non-human primate (Microcebus murinus)
Stéphanie G. Trouche, Allal Boutajangout, Ayodeji A. Asuni…·Nadine Mestre‐Francés
This study evaluates the safety and efficacy of an Aβ derivative vaccine in aged non-human primates, finding reduced intracellular Aβ and trends of cognitive improvement without adverse effects.