Queuine, a bacterial derived hypermodified nucleobase, shows protection in in vitro models of neurodegeneration
Patricia Richard, Xavier Manière, Lucie Kozlowski, Hélène Guillorit, Patrice Garnier, Antoine Danchin, Nicole C. McKnight
This study shows that the bacterial-derived compound STL-101 (queuine) protects neurons in vitro by reducing alpha-synuclein and tau hyperphosphorylation in neurodegenerative models.
PLoS ONE · Aug 11, 2021Peer-reviewedNeuroscience