Committed hemopoietic progenitors, not stem cells, are the principal responders to Hox gene transduction
Harvey Lim, Salima Janmohamed, Patricia Benveniste, Robert Herrington, Mary Barbara, Catherine Frelin, Deborah Hyam, Christopher J. Paige, Juan-Carlos Zuñiga-Pflücker, Carol Stocking, Jana Krosl, Guy Sauvageau, Norman N Iscove
The paper shows that committed progenitors, not stem cells, respond to Hox gene transduction by showing self-renewal and reconstituting potential.
bioRxiv · Aug 10, 2017 · PreprintCell Biology