Author

Patrick Bosco

Columbia University Irving Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:dimensionality reduction· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Andrew A. SprouliD· 1 shared Aomeng CuiiD· 1 shared Dritan AgalliuiD· 1 shared Emily RichtersiD· 1 shared Paula Barrilero Delgado· 1 shared Ronak PateliD· 1 shared Uğur AkcaniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Andrew A. SproulORCID

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1 paper

Recent·Most cited

Generation of hiPSC-derived brain microvascular endothelial cells using a combination of directed differentiation and transcriptional reprogramming strategies

Aomeng Cui, Ronak Patel, Patrick Bosco, Uğur Akcan, Emily Richters, Paula Barrilero Delgado, Dritan Agalliu, Andrew A. Sproul

This paper generates and characterizes reprogrammed brain microvascular endothelial cells from hiPSCs using transcription factors FOXF2 and ZIC3, showing improved BBB properties and integration with neural cells in a 3D system.

bioRxiv · Apr 3, 2024 · PreprintNeuroscience