Author

Pattama Wapeesittipan

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Biophysics· 1

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Research Focus:chromatin & epigenetic regulation· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1

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Antonia S. J. S. MeyiD· 1 shared Julien MicheliD· 1 shared Malcolm D. WalkinshawiD· 1 shared

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2018-2018 · peak 1/yr

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1 shared paperBiophysics

Antonia S. J. S. MeyORCID

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintOct 10, 2018

Allosteric effects in catalytic impaired variants of the enzyme cyclophilin A may be explained by changes in nano-microsecond time scale motions

Pattama Wapeesittipan, Antonia S. J. S. Mey, Malcolm D. Walkinshaw, Julien Michel

This study uses MD simulations to show that catalytic impairment in CypA mutants is linked to faster nano-microsecond motions of Phe113, challenging the role of millisecond-scale conformational changes in allosteric effects.

DOI 10.1101/224329

mechanistic / dynamical modelchromatin & epigenetic regulation

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