Engineered tRNA suppression of a CFTR nonsense mutation
John D. Lueck, Daniel T. Infield, Adam L. Mackey, R. Marshall Pope, Paul B. McCray, Christopher A. Ahern
This paper demonstrates the use of engineered tRNA to suppress a CFTR nonsense mutation, rescuing full-length protein function in a cystic fibrosis model.
bioRxiv · Nov 20, 2016 · PreprintCell Biology