Author

Adam L. Mackey

University of Iowa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Christopher A. AherniD· 2 shared Alfredo Perales‐PuchaltiD· 1 shared Daniel T. InfieldiD· 1 shared Daniel T. Infield· 1 shared David B. WeineriD· 1 shared Jae Seok YooniD· 1 shared John D. LueckiD· 1 shared John D. Lueck· 1 shared

Activity by Year

2016-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMolecular Biology

Christopher A. AhernORCID

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2 papers

Recent·Most cited

Engineered transfer RNAs for suppression of premature termination codons

John D. Lueck, Jae Seok Yoon, Alfredo Perales‐Puchalt, Adam L. Mackey, Daniel T. Infield, Mark A. Behlke, Marshall R. Pope, David B. Weiner, William R. Skach, Paul B. McCray, Christopher A. Ahern

This paper identifies engineered transfer RNAs (ACE-tRNA) that suppress premature termination codons in mammalian cells and mice, showing high suppression activity for common disease-causing nonsense codons.

Nature Communications · Feb 18, 2019Peer-reviewedMolecular Biology

Engineered tRNA suppression of a CFTR nonsense mutation

John D. Lueck, Daniel T. Infield, Adam L. Mackey, R. Marshall Pope, Paul B. McCray, Christopher A. Ahern

This paper demonstrates the use of engineered tRNA to suppress a CFTR nonsense mutation, rescuing full-length protein function in a cystic fibrosis model.

bioRxiv · Nov 20, 2016 · PreprintCell Biology