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Paul D. Sniegowski

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Evolutionary Biology· 1

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Approach:statistical model· 1

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Philip J Gerrish· 1 shared Sophie Penisson· 1 shared Tanya Singh· 1 shared

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2016-2016 · peak 1/yr

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1 shared paperEvolutionary Biology

Philip J Gerrish

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Evolutionary BiologybioRxivAug 8, 2016

Dynamics and fate of beneficial mutations under lineage contamination by linked deleterious mutations

Sophie Penisson, Tanya Singh, Paul D. Sniegowski, Philip J Gerrish

The paper models the dynamics of beneficial mutations under lineage contamination by linked deleterious mutations, finding that survival probabilities are modified by a correction factor and that there is an optimal deleterious mutation rate for maximizing beneficial mutation production.

DOI 10.1534/genetics.116.194597

statistical model

𝕏 PostBluesky