Quantitative cross-linking/mass spectrometry reveals subtle protein conformational changes
Zhuo Angel Chen, Lutz Fischer, Salman Tahir, Jimi-Carlo Bukowski-Wills, Paul N. Barlow, Juri Rappsilber
This study develops QCLMS to detect protein conformational changes by analyzing cross-linking yields and introduces methods to distinguish minor and major changes.
Wellcome Open Research · Nov 15, 2016Peer-reviewedBiochemistry