Paul O’Neill

The paper characterizes expressed transcripts in the human cortex across development, identifying novel coding sequences with clinical relevance.

The paper uses long-read transcript sequencing to identify differential isoform expression in the entorhinal cortex of tau transgenic mice, revealing novel isoforms and transcript associations with tau pathology.

This study identifies transcriptional changes in tau and amyloid mouse models, revealing gene expression patterns linked to AD pathology and immune response.