A critical role for E2-p53 interaction during the human papillomavirus 16 life cycle
Christian T. Fontan, Claire D. James, Molly L. Bristol, Apurva Tadimari Prabhakar, Raymonde O. Otoa, Xu Wang, Elmira Karimi, Pavithra Rajagopalan, Devraj Basu, Iain M. Morgan
This study shows that the E2-p53 interaction is critical for HPV16 life cycle, with disruption leading to anti-viral effects like reduced proliferation and increased DNA damage.
bioRxiv · Nov 1, 2021 · PreprintMolecular Biology