BiophysicsStructurePeer-reviewed
PAS domain of flagellar histidine kinase FlrB exhibits novel architecture, and binds Heme as sensory signal in unconventional fashion
Peeali Mukherjee, Shubhangi Agarwal, Sritapa Basu Mallick, Jhimli Dasgupta
The paper reports the crystal structure of FlrB's PAS domain and identifies heme as a sensory ligand, showing synergistic binding with ATP to regulate flagellar gene transcription in Vibrio cholerae.