Radiation exposure induced blood-brain barrier injury via mitochondria-mediated sterile inflammation
Peng Wang, Jiayue Liu, Min Zhang, Juan Yang, Peihan Lian, Xiu Cheng, Jianhua Qin
This study uses a blood-brain barrier microphysiological system to show radiation induces sterile inflammation via mitochondrial DNA release and cGAS-STING signaling, with potential therapeutic targets identified.
Advanced Science · May 28, 2025Peer-reviewedNeuroscience