Functional analysis of KIT gene structural mutations causing porcine dominant white phenotype by using genome edited mouse models
Guanjie Sun, Xinyu Liang, Ke Qin, Yufeng Qin, Xuan Shi, Peiqing Cong, Delin Mo, Xiaohong Liu, Yaosheng Chen, Zuyong He
The paper creates genome-edited mouse models to study KIT gene mutations in pigs and finds that only the combination of two structural mutations causes a dominant white phenotype.
Frontiers in Genetics · Mar 3, 2020Peer-reviewedMolecular Biology