Yaosheng Chen

The paper performs a multi-breed meta-GWAS in pigs to identify genomic regions associated with complex traits and integrates with PigGTEx to prioritize variant-gene-tissue-trait circuits.

The paper identifies a causative SNP in the promoter of myogenin that influences myogenic differentiation and muscle regeneration in pigs.

The paper presents PigGTEx, a resource linking genetic variants to transcriptomic phenotypes in pigs, showing pigs' similarity to humans in gene regulation and complex traits.

This study identifies selection signatures and loci associated with complex traits in pigs by analyzing multi-omics data from Eastern and Western breeds.

The paper creates genome-edited mouse models to study KIT gene mutations in pigs and finds that only the combination of two structural mutations causes a dominant white phenotype.

This study shows that BMP15 is essential for porcine ovarian and follicular development, as its knockdown leads to reduced fertility and ovarian dysfunction.