Analysis of hepatic lentiviral vector transduction; implications for preclinical studies and clinical gene therapy protocols.
Peirong Hu, Yajing Hao, Wei Hua Tang, Graham H. Diering, Fei Zou, Tal Kafri
The paper characterizes hepatic lentiviral vector transduction in mice, finding strain-specific variations and QTLs linked to transduction efficiency and kinetics, suggesting the need for personalized gene therapy protocols.
Viruses · Feb 17, 2025Peer-reviewedGenetics