Proteomics Reveals Extracellular Matrix Injury in the Glomeruli and Tubulointerstitium of Kidney Allografts with Early Antibody-Mediated Rejection
Sergi Clotet‐Freixas, Caitríona M. McEvoy, Ihor Batruch, Chiara Pastrello, Max Kotlyar, Julie A.D. Van, Madhurangi Arambewela, Alex Boshart, Sofia Farkona, Yun Niu, Yanhong Li, Olusegun Famure, Andrea Božović, Vathany Kulasingam, Peixuen Chen, , Ana Konvalinka
The paper uses proteomics to identify ECM injury in kidney allografts with early AMR, finding decreased ECM proteins and increased LGALS1 and GSTO1 in affected tissues.
Journal of the American Society of Nephrology · Sep 8, 2020Peer-reviewedMolecular Biology