HaloTrace: A spatiotemporally precise fluorescent readout of blood-brain barrier permeability in mice
Hannah L. Zucker, Ekaterina Konshina, Perry Mitchell, Chenghua Gu
HaloTrace provides a spatiotemporal readout of BBB permeability in mice by using a fluorescent ligand that specifically accumulates in the brain at sites of BBB dysfunction.
bioRxiv · Oct 30, 2025 · PreprintNeuroscience