Ultra-High Resolution Solid-State NMR for High Molecular Weight Proteins on GHz-Class Spectrometers
Songlin Wang, Thirupathi Ravula, John A. Stringer, Peter L. Gor’kov, Owen A. Warmuth, Christopher G. Williams, Alex F. Thome, Leonard J. Mueller, Chad M. Rienstra
This study improves solid-state NMR resolution for high molecular weight proteins using GHz-class spectrometers and novel techniques, achieving better than 0.2 ppm resolution for proteins up to 144 kDa.
Science Advances · Jul 23, 2025Peer-reviewedBiophysics