Inhibition of NLRP3 Differentially Regulates Blood Pressure and Inflammation in Male versus Female DOCA-Salt Sprague Dawley Rats
Cameron M. Liss, Ahmed A. Elmarakby, Kelly Sullivan, Peyton R. Hanson, Kasey Belanger, Riyaz Mohamed, David L. Mattson, Erin B. Taylor, Michael James Ryan, Jennifer C. Sullivan
This study shows that NLRP3 inhibition reduces blood pressure in male DOCA-salt rats but not females, while decreasing T cell levels in both sexes.
bioRxiv · Mar 20, 2026 · PreprintPhysiology