Synergising single-cell resolution and 4sU labelling boosts inference of transcriptional bursting
David M. Edwards, Philip Davies, Daniel Hebenstreit
The paper introduces a Bayesian model to analyze 4sU scRNA-seq data, improving inference of transcriptional bursting parameters and their relationship with histone modifications.
Genome biology · Jun 16, 2023Peer-reviewedBioinformatics