Author

David M. Edwards

University of WarwickORCID 0000-0002-7250-2099Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:Bayesian inference· 1 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Daniel HebenstreitiD· 2 shared Anand Kumar SinghiD· 1 shared Claus M. AzzaliniD· 1 shared Emily M Price· 1 shared Francesco Falciani BiD· 1 shared Hannah L Dixon· 1 shared Jianming WangiD· 1 shared Kayoko TanakaiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Daniel HebenstreitORCID

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2 papers

Recent·Most cited

Synergising single-cell resolution and 4sU labelling boosts inference of transcriptional bursting

David M. Edwards, Philip Davies, Daniel Hebenstreit

The paper introduces a Bayesian model to analyze 4sU scRNA-seq data, improving inference of transcriptional bursting parameters and their relationship with histone modifications.

Genome biology · Jun 16, 2023Peer-reviewedBioinformatics

Genome-wide chromosomal association of Upf1 is linked to Pol II transcription in Schizosaccharomyces pombe

Sandip De, David M. Edwards, Vibha Dwivedi, Jianming Wang, Wazeer Varsally, Hannah L Dixon, Anand Kumar Singh, Precious O. Owuamalam, Matthew T Wright, R. Summers, Md Nazmul Hossain, Emily M Price, Marcin Wlodzimierz Wojewodzic, Francesco Falciani B, Nikolas John Hodges, , Saverio Brogna

This paper reports genome-wide ChIP data showing Upf1 associates with active genes in S. pombe, correlating with Pol II transcription and mRNA levels, and reveals transcriptional defects in Upf1-deficient cells.

Nucleic Acids Research · Dec 6, 2021Peer-reviewedMolecular Biology