Neuronal histone methyltransferase EZH2 regulates neuronal morphogenesis, synaptic plasticity, and cognitive behavior of mice
Mei Zhang, Yong Zhang, Qian Xu, Joshua A. Crawford, Cheng Qian, Guohua Wang, Eastman M. Lewis, Philip Hall, Gül Dölen, Richard L. Huganir, Jiang X. Qian, Xinzhong Dong, Mikhail V. Pletnikov, Chang-Mei Liu, Feng‐Quan Zhou
This study shows that neuronal EZH2 regulates neuronal morphogenesis and cognitive behavior in mice by controlling gene expression and dendritic spine density.
bioRxiv · Mar 20, 2019 · PreprintNeuroscience