Feng‐Quan Zhou

This study investigates the roles of Kdm6a and Kdm6b in neural regeneration, finding they regulate axon regeneration and RGC survival with distinct mechanisms and identifying Klf4 as a downstream target.

The paper constructs an intercellular communication atlas of the retina, identifying Oprm1 as a neuroprotective factor that enhances RGC survival through ligand-receptor interactions.

This study shows Ezh2 promotes axon regeneration in the PNS and CNS by epigenetically regulating genes involved in regeneration and inhibitory signaling.

This study shows that overexpressing Ascl1 promotes optic nerve regeneration and retinal ganglion cell survival in mice by activating Sox11.

The paper uses scRNA-seq to identify subtype-specific transcriptomic changes in DRG neurons of Pirt-EGFPf mice under neuropathic pain conditions.

LRLoop identifies bidirectional ligand-receptor feedback loops in cell-cell communication, reducing false positives and revealing new interactions in retinal development.

This study identifies UCHL1 as a facilitator of NSC activation post-SCI by clearing protein aggregates, and shows that C3/C3aR signaling suppresses UCHL1 and NSC activation.

This study shows ALKBH1 demethylates N6-mA in sensory neurons, promoting axon regeneration by regulating neurodevelopmental genes.

This study shows that knocking out myosin IIA/B in retinal ganglion cells promotes optic nerve regeneration, with synergistic effects when combined with Lin28 overexpression.

The paper identifies TERT and p53 as regulators of axon regeneration downstream of c-Myc in the CNS and PNS, showing p53 overexpression promotes regeneration.

This study shows that neuronal EZH2 regulates neuronal morphogenesis and cognitive behavior in mice by controlling gene expression and dendritic spine density.

This study identifies Lin28a and Lin28b as key regulators of axon regeneration in mammals, showing their ability to promote optic nerve regeneration through miRNA regulation and interaction with PTEN.