SMARCA4 Mutations in KRAS-mutant Lung Adenocarcinoma: A Multi-cohort Analysis
Liang Liu, Tamjeed Ahmed, William Jeffrey Petty, Stefan C. Grant, Jimmy Ruiz, Thomas William Lycan, Ümit Topaloĝlu, Ping‐Chieh Chou, Lance David Miller, Gregory A. Hawkins, Martha A. Alexander‐Miller, Stacey S. O’Neill, Bayard L. Powell, Ralph B. D’Agostino, Reginald F. Munden, , Wei Zhang
This study analyzes SMARCA4 mutations in KRAS-mutant lung adenocarcinoma across multiple cohorts, finding adverse clinical outcomes associated with SMARCA4 mutations in both non-immunotherapy and immunotherapy-treated patients.
Molecular Oncology · Oct 26, 2020Peer-reviewedGenetic & Genomic Medicine