Author

Pleuni Pennings

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alison L Hill· 1 shared Ben Wilson· 1 shared Daniel I.S. Rosenbloom· 1 shared Dmitri A. Petrov· 1 shared Dmitri Petrov· 1 shared Martin A Nowak· 1 shared Stefany Moreno-Gamez· 1 shared

Activity by Year

2014-2016 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 11 mutual co-author links

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1 shared paperEvolutionary Biology

Alison L Hill

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2 papers

Recent·Most cited

Soft selective sweeps in evolutionary rescue

Ben Wilson, Pleuni Pennings, Dmitri Petrov

The paper analyzes evolutionary rescue scenarios, finding that soft selective sweeps, where multiple adaptive mutations spread simultaneously, are common when rescue is likely.

bioRxiv · May 12, 2016Evolutionary Biology

Imperfect drug penetration leads to spatial monotherapy and rapid evolution of multi-drug resistance

Stefany Moreno-Gamez, Alison L Hill, Daniel I.S. Rosenbloom, Dmitri A. Petrov, Martin A Nowak, Pleuni Pennings

The paper models how imperfect drug penetration creates spatial monotherapy, accelerating multi-drug resistance evolution in infections.

bioRxiv · Dec 19, 2014Evolutionary Biology