An Epstein-Barr virus-encoded snoRNA directs 2'-O-methylation of human rRNAs to control translation and the viral lytic switch
Yarden Dan, Beáta E. Jády, Yudit Halperin, Yuval Nevo, Aliza Fedorenko, Anat Bashan, Maram Arafat, Pnina Glick, Ada Yonath, Tamás Kiss, Daphna Nachmani
This study identifies v-snoRNA1 as an EBV-encoded RNA that directs 2'-O-methylation of host rRNAs, affecting translation and viral lytic switch.
Cell Reports · Aug 28, 2026Peer-reviewedMolecular Biology