Author

Daphna Nachmani

Hebrew University of JerusalemORCID 0000-0002-8489-9986Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Bioinformatics· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

Yudit HalperiniD· 3 shared Maram ArafatiD· 2 shared Ada YonathiD· 1 shared Adi Reches· 1 shared Alexander van OudenaardeniD· 1 shared Aliza Fedorenko· 1 shared Anat BashaniD· 1 shared Beáta E. Jády· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersMolecular Biology

Yudit HalperinORCID

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Author profile →

4 papers

Recent·Most cited

An Epstein-Barr virus-encoded snoRNA directs 2'-O-methylation of human rRNAs to control translation and the viral lytic switch

Yarden Dan, Beáta E. Jády, Yudit Halperin, Yuval Nevo, Aliza Fedorenko, Anat Bashan, Maram Arafat, Pnina Glick, Ada Yonath, Tamás Kiss, Daphna Nachmani

This study identifies v-snoRNA1 as an EBV-encoded RNA that directs 2'-O-methylation of host rRNAs, affecting translation and viral lytic switch.

Cell Reports · Aug 28, 2026Peer-reviewedMolecular Biology

A unified analysis of cell-type and trajectory-associated pathways in single-cell data using Phoenix

Yudit Halperin, Daphna Nachmani, Michal Rabani

Phoenix identifies cell-type and trajectory-associated pathways in single-cell data using random forest models and non-parametric testing, outperforming existing tools in capturing small pathway activities and revealing cross-species overlaps.

Genome Research · Aug 1, 2026Peer-reviewedBioinformatics

Dynamic Ribosomal RNA Methylation Regulates Translation in the Hematopoietic System and is Essential for Stem Cell Fitness

Ofri Rabany, Sivan Ben Dror, Maram Arafat, Hadar Aharoni levitanus, Yudit Halperin, Virginie Marchand, Nikolai Romanovski, Noga Ussishkin, Maayan Livneh Golany, Adi Reches, Judith Wexler, Nina Mayorek, Galia Monderer-Rothkoff, Sagiv Shifman, Widad Mâmmer Bouhou, , Daphna Nachmani

The paper identifies rRNA methylation dynamics as a mechanism regulating translation efficiency and HSC fitness during hematopoietic differentiation.

Blood · Nov 5, 2025Peer-reviewedMolecular Biology

Separation of telomere protection from length regulation by two different point mutations at amino acid 492 of RTEL1

Riham Smoom, Catherine Lee May, Dan Lichtental, Kamil Bar-Ness, Reina Rangel, Johad Khoury, Daphna Nachmani, Dana Avrahami, Farida Ahangari, Emmanuel Skordalakes, Naftali Kaminski, Klaus H. Kaestner, Yehuda Tzfati

This study introduces two RTEL1 mouse models with distinct mutations at amino acid 492, showing that M492K affects telomere length while M492I impairs telomere protection, leading to different disease phenotypes.

Nucleic Acids Research · May 29, 2025Peer-reviewedGenetics